murali krishna kumar muthyala

Asst. Professor,

DEPARTMENT OF PHARMACEUTICAL SCIENCES

Educational Qualifications

Post Graduation

2001 - M.Pharmacy, Andhra University

Under Graduation

1999 - B.Pharmacy, JNTU, Hyderabad

Doctoral Details

  • Received PhD for work on Bioactive secondary metabolites from marine organisms: Chemical and biological analysis of the marine sponges Hyatella cribriformis and Dendrilla nigra of the Indian Ocean under Prof. D.Venkata Rao( Andhra University ),Prof. B.S.Sastry( Andhra University )Awarded on 07-06-2006 .

Scholarships,Honors & Awards

Awards

    Others

    • SRF by MoES, New Delhi , -4.

    Scholorship

    • MERIT FELLOWSHIP by UGC, New Delhi , -2.

    Professional Experience

    • Lecturer , BITS-Pilani, Rajasthan from 21-07-2007 to 28-09-2008.

    Adminstrative Experience

    • Placement officer , AU College of Pharmaceutical Sciences, Andhra University from 01-07-2014 to Till date.
    • Warden , Andhra UNiversity from 19-08-2014 to 06-25-2017.
    • ASSOCIATE DIRECTOR , NMR RESEARCH CENTER from 04-06-2017 to Till date.

    Courses Taught

    • Organic CHemistry-II for B.PHARM-BACHELOR OF PHARMACY (2-1) at UG level for the academic year 2014-2015.
    • Applied Biochemistry for B.PHARM-BACHELOR OF PHARMACY (2-2) at UG level for the academic year 2014-2015.
    • Medicinal CHemistry-I for B.PHARM-BACHELOR OF PHARMACY (3-1) at UG level for the academic year 2014-2015.
    • Chemistry of Natural Products for B.PHARM-BACHELOR OF PHARMACY (4-1) at UG level for the academic year 2014-2015.
    • Medicinal CHemistry-II for B.PHARM-BACHELOR OF PHARMACY (4-2) at UG level for the academic year 2014-2015.
    • Advanced Organic CHemistry for M.PHARM - PHARMACEUTICAL CHEMISTRY (REGULAR) (1-1) at PG level for the academic year 2014-2015.
    • Chemistry of Natural Products for M.PHARM - PHARMACEUTICAL CHEMISTRY (REGULAR) (1-1) at PG level for the academic year 2014-2015.
    • Advanced Medicinal Chemistry for M.PHARM - PHARMACEUTICAL CHEMISTRY (REGULAR) (1-2) at PG level for the academic year 2014-2015.
    • Modern Analytical techniques for M.PHARM - PHARMACEUTICAL CHEMISTRY (REGULAR) (1-2) at PG level for the academic year 2014-2015.

    Academic Guidance

    • "Synthesis and evaluation of 2-acyl thiazolidine carboxylic acids as new antimicrobial agents", Sarita, AWARDED , 2009 .
    • "Isolation and identification of bioactive compounds from selected medicinal plants", Vasudeva Rao, AWARDED , 2009 .
    • "Synthesis and Biological Evaluation of Phenothiazine Chalcones", P.Raghuveer, AWARDED , 2010 .
    • "Synthesis and Biological Evaluation of thiazolidine carboxylic acids", B.N.B. Vaidehi, AWARDED , 2010 .
    • "Phytochemical, microbiological and antioxidant investigation on the bark of Chloroxylon swertenia ", Subba Lakshmi, AWARDED , 2010 .
    • "Drugs from deep: Marine spopnges as a source of novel bioactive molecules", O.Veerkumar Reddy, AWARDED , 2010 .
    • "Computational evaluation and modelling of COX-2 drug databases", A.Vasudevarao, AWARDED , 2010 .
    • "LPIIDF studies of marine protein kinase enzyme inhibitoprs", M Haneesha, AWARDED , 2011 .
    • "Development of novel anti-inflammatory molecules from marine natural product database by inverse induced fit docking", Sangeetha, AWARDED , 2011 .
    • "Chemical and biological studies on the seeds of Piper longum", Mounika, AWARDED , 2011 .
    • "LIGAND PROTEIN INVERSE FIT DOCKING OF BRIARANE DITERPENOIDS", Shalini, AWARDED , 2011 .
    • "Synthesis and biological evaluation of some novel chalcones", Snadeep, AWARDED , 2011 .
    • "Development of novel CDK inhibitors from LPIIDF studies on marine natural product databases", Kavitha, AWARDED , 2012 .
    • "FBDD and ligand optimization studies for development of novel MAP kinase 3 inhibitors", Ismail Mujhavar, AWARDED , 2012 .
    • "Synthesis and biological evaluation of some novel pthalimide derivatives", Apoorva, AWARDED , 2013 .
    • "DISCOVERY OF NEW LEADS FOR RESISTANT MUTANT FORMS OF BCR-ABL KINASE BY STRUCTURE BASED VIRTUAL SCREENING USING MARINE NATURAL PRODUCT DATABASE", A.Srinath Raju, AWARDED , 2013 .
    • "Repurposing of drugs: vROCS based screening and identification of selective antitubercular agents from drug database", Pradeep Kumar, AWARDED , 2013 .
    • "Shape Based Virtual Screening and Identification of non-antibiotics as Antitubercular agents", T Shruti, AWARDED , 2014 .
    • "Synthesis and evaluation of N-aryl maleimide derivatives", Swati, AWARDED , 2014 .
    • "Synthesis and antimicrobial evaluation of benzimidazole derivatives", M.Sowmya, AWARDED , 2014 .

    Journal Publications

    • "Shape Based Virtual Screening and Discovery of Potential Antitubercular activity in ‘Non-antibiotics’" in 0975-8275 International Journal of Drug Design and Discovery
    • "Synthesis and screening of new maleimide derivatives as potential antitubercular agents" in 2231-3354 Journal of Applied Pharmaceutical Sciences
    • "Rubrolide R: A new furanone metabolite from the ascidian Synoicum of the Indian Ocean" in 1478-6419 Natural Products Research
    • "Denigrins A-C: New antitubercular 3,4-diarylpyrrole alkaloids from Dendrilla nigra" in 1478-6419 Natural Products Research
    • "3D QSAR Analysis of 2-(Substituted Aryl)-Thiazolidine-4-Carboxamides as Potent Antitubercular Agents" in 1573-4099 Current Computer-Aided Drug Design
    • "Design, synthesis, and preliminary in vitro and in vivo pharmacological evaluation of 4-{4-[2-(4-(2-substitutedquinoxalin-3-yl)piperazin-1-yl)ethyl]phenyl}thiazoles as atypical antipsychotic agents" in 1054-2523 Med Chem Res
    • "Actinomycin “D” from marine sediment associated Streptomyces capillispiralis mtcc10471" in Asian J PRHC
    • "Novel Pyridinium compound from marine actinomycete, Amycolatopsis alba var.nov. DVR D4 showing antimicrobial and cytotoxic activities in vitro" in 0944-5013 Microbiological Research
    • "AUDocker LE: A GUI for virtual screening with AUTODOCK Vina" in 1756-0500 BMC Research Notes
    • "Design, synthesis, and preliminary in vitro and in vivo pharmacological evaluation of 2-{4-[4-(2,5-disubstituted thiazol-4-yl)phenylethyl]piperazin-1-yl}-1,8-naphthyridine-3- carbonitriles as atypical antipsychotic agents" in 1475-6366 Journal of Enzyme Inhibition and Medicinal Chemistry
    • "Denovo based ligand genereation and docking studies of PPAR δ agonists. Correlations between predicted bioloticalactivity vs. Biopharmaceutical descriptors" in 1347-0442 Chem-Bio Informatics Journal
    • "Computer assisted molecular docking and 3D QSAR studies on 1,3,5-trisubstituted aryls as PPAR agonists" in 0974-4304 Int.J.Pharm.Tech
    • "Synthesis and preliminary screening of novel N-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}acetamides as potential atypical antipsychotic agents" in 1475-6366 J. Enzyme Inhib. Med. Chem
    • "A New scalaranesesterterpenes from the marine sponge Hyatellacribriformisof the Indian Ocean" in 0975-0983 Ind. J Chem
    • "Synthesis of N-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}acetamides as novel atypical antipsychotics" in 0960-894X Bioorg.Med.Chem.Lett
    • "Antimicrobial activity of the plant Schyzyziumalternifolium" in 0975-427X Asian J. Chem
    • "New sphingolipids and a sterol from a Lobophytumspecies of the Indian Ocean" in 1347-5223 / 0009-2363 Chem.Pharm.Bull
    • "Chemical constituents of a marine sponge Echinodictyumgorgonoides" in 1091-6490 Proceedings of Ap. Acad. of Sci
    • "A new scalaranesesterterpene derivative from the marine sponge Hyatellacribriformisof Indian Ocean" in 1091-6490 Proceedings of Ap. Acad. of Sci
    • " A new sphingolipid from the gorgonian Junceellajuncea of the Indian Ocean" in 1478-6419 Nat. Prod. Res
    • "Newsphingosine derivatives from the Indian Ocean Gorgonian Pseudopterogorgiaaustraliensis" in 0974-5211 J. Nat. Prod
    • "Juncenolide B, A New briarane diterpene from the gorgonian Junceella juncea of the Indian Ocean" in 0975-427X Asian J. Chem.,
    • "New sphingolipids from a marine sponge Iotrochota baculifera" in 1347-5223 / 0009-2363 Chem.Pharm.Bull

    Conference Papers

    • International Conference "New frontiers in Marine Natural Product Research (NFMNPR)" Presentation at National Institute of Oceanography, Goa, India .
    • International Conference "12th International Conference on the Interface of Chemistry-Biology in Biomedical Research " Presentation at BITS, Pilani, India .
    • International Conference "workshop on Molecular modeling and drug design " Presentation at university of Hyderabad, Hyderabad,.

    Book Published

    • Wrote Studies in NAtural Products Book Chapter 8 Protein Kinase Inhibitors from Microorganisms type : ISBN Number : 978-0-444-63460-3 Co-authored byDR. P RADHIKA( Andhra University ) in 2015.

    Research Projects

    • Synthesis and screening of novel lamellarin analogues as potential agents against Mycobacterium tuberculosis, Funding Agency : DST-SERB, Starting Date : 10/10/2015.

    Additional Info